biotechnology summary The fusion of flesh and machine is trend which, although inscribed in the history of modern technology from its beginnings, has reached a unprecedented momentum in recent years as a result of crucial advances in information technology, biology, and the development of global networks. Consequently, doubts are emerging concerning the viability of a distinct and definable human nature. Historical and social theories and concepts are being unhinged by the spread hybrids and by new forms of artificial life which are likely to trigger social changes escaping the grip of calculation. Attempts to defend an essential human nature against technical hybridisation, rather than strengthening the human subject, may have further blurred the question of historical subjectivity. Large amounts of money are invested into research and development of artifical biology, making some of the predictions of AI and robotics experts about radical and far reaching changes a matter of time.

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Introduction: The Substitution of Human Faculties with Technology: Artificial Intelligence and Expert Systems Research in artificial intelligence, starting in the 1960s, yet formulated a new goal: the automation of thought processes with intelligent machines. Although first attempts to develop "thinking" machines had only little success as the aimed at solving very general problems, the invention of expert systems marked a breakthrough. Albeit the application of those semi-intelligent systems is (still) restricted to quite narrow domains of performance, such as taxation and medical image interpretation, they are able to mimic the knowledge and reasoning capabilities of an expert in a particular discipline. While the development of intelligent machines, which are able to reason, to generalize and to learn from past experience is not likely to become reality in the very near future, research in artificial intelligence progresses quickly and sooner or later the substitution of men's unique faculties will come true.

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1970s: Computer-Integrated Manufacturing (CIM) Since the 1970s there had been a growing trend towards the use of computer programs in manufacturing companies. Especially functions related to design and production, but also business functions should be facilitated through the use of computers. Accordingly the CAD/CAM technology, related to the use of computer systems for design and production, was developed. CAD (computer-aided design) was created to assist in the creation, modification, analysis, and optimization of design. CAM (computer-aided manufacturing) was designed to help with the planning, control, and management of production operations. CAD/CAM technology, since the 1970s, has been applied in many industries, including machined components, electronics products, equipment design and fabrication for chemical processing. To enable a more comprehensive use of computers in firms the CIM (computer-integrated manufacturing) technology, which also includes applications concerning the business functions of companies, was created. CIM systems can handle order entry, cost accounting, customer billing and employee time records and payroll. The scope of CIM technology includes all activities that are concerned with production. Therefore in many ways CIM represents the highest level of automation in manufacturing.

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Above.net Headquartered in San Jose, USA, AboveNet Communications is a backbone service provider. Through its extensive peering relationships, the company has built a network with the largest aggregated bandwidth in the world. http://www.above.net

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Celera Celera is an American company dedicated to the full sequencing and exploitation of the humane genome according to private business criteria. The company whose slogan is "Speed matters", is run by the Vietnam veteran Craig Ventor, whose declarations and business practices have given rise to widespread criticism. Unlike the Humane Genome Project, which is mapping the entire genome, Dr Ventor's method focuses on the genome information contained in messenger molecules. In keeping with Celera's slogan, this allows a much faster sequencing rate. The aggressive manoeuvring of Celera, coupled with Dr Ventor's unchecked self-esteem which lead him to compare himself to Nobel Prize winners, has meant that Dr. Ventor has been ostracised within the scientific community. James Watson, the co-discoverer of DNA, refers to Dr. Ventor's fast but relatively crude results as work that "any monkey could do" (source: BBC) http://www.celera.com

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Agostino Ramelli's reading wheel, 1588 Agostino Ramelli designed a "reading wheel" which allowed browsing through a large number of documents without moving from one spot. Presenting a large number of books, a small library, laid open on lecterns on a kind of ferry-wheel, allowing us to skip chapters and to browse through pages by turning the wheel to bring lectern after lectern before our eyes, thus linking ideas and texts together, Ramelli's reading wheel reminds of today's browsing software used to navigate the World Wide Web.

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