900 B.C.
A postal service is used for governmental purposes in China.
500 B.C.
In ancient Greece trumpets, drums, shouting, beacon, fires, smoke signals, and mirrors are used for message transmission.
4th century B.C.
Aeneas Tacitus, a Greek military scientist and cryptographer, invented an optical communication system that combines water and beacon telegraphy. Torches indicated the beginnings and the ends of a message transmission while water jars were used to transmit the messages. These jars had a plugged standard-size hole drilled on the bottom side and were filled with water. As those who sent and those who received the message unplugged the jars simultaneously, the water drained out. Because the transmitted messages corresponded to water levels, the sender indicated by a torch signal that the appropriate water level had been reached. The methods disadvantage was that the possible messages were restricted to a given code, but as the system was mainly used for military purposes, this was offset by the advantage that it was almost impossible for outsiders to understand the messages unless they possessed the codebook.
With communication separated from transportation, the distant became near. Tacitus' telegraph system was very fast and not excelled until
For further information see Joanne Chang & Anna Soellner, Decoding Device,
3rd century B.C.
Wax tablets are used as writing material in Mesopotamia, ancient Greece, and Etruria.
2nd century B.C.
In China paper is invented.
1st century B.C.
The use of codices instead of scrolls - basically the hardcover book as we know it today - is an essential event in European history. To quote accurately by page number, to browse through pages and to skip chapters - things that were impossible when reading scrolls - becomes possible.
In the computer age we are witnesses to a kind of revival of the scrolls as we scroll up and down a document. The introduction of hypertext possibly marks the beginning of a similar change as has taken place with the substitution of scrolls with codices.
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With the introduction of the printing press into England in 1476 printing was made easier and faster and made copies less expensive. By the early 16th century two trades dominated the industry: independent printers and booksellers or stationers many of whom were vertically integrated as printers. At the time, the Crown was concerned about sedition and the Church about heresy. In 1557 by royal charter the Stationers' Company of London was created and exclusive rights granted. Approved printers were given the right to copy approved works. Accordingly the roots of copyright were censorship.
The Statute of Queen Ann, the first formal copyright law, was passed in 1710. Copyright was then conferred on the author of a work, but still the owner of copyright was nearly always the bookseller. Only in 1775 the House of Lords replaced the common law of printing rights in favor of the author.
In this tradition the underlying concept of copyright is monopoly, first granted to printers, then to booksellers and later to individual creators. Copyright is treated as a commodity to be bought and sold and inspired by a need to protect the public from the power of the artist.
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Merck & Co. is a research-driven pharmaceutical company that discovers, develops, manufactures and markets a broad range of human and animal health products, and provides pharmaceutical benefit services through Merck-Medco Managed Care LLC. The Company is comprised of two operating segments. Merck-Medco primarily includes sale of non-Merck products and Merck-Medco pharmaceutical benefit services, principally manages prescription drug programs and programs to help manage patient health. Merck-Medco sells its services to corporations, labor unions and insurance companies. Merck Pharmaceuticals consists of therapeutic and preventive agents, generally sold by prescription, for the treatment of human disorders. The Company's human health products are sold to drug wholesalers and retailers, hospitals, clinics, government agencies, and managed care providers.
Expert systems are advanced computer programs that mimic the knowledge and reasoning capabilities of an expert in a particular discipline. Their creators strive to clone the expertise of one or several human specialists to develop a tool that can be used by the layman to solve difficult or ambiguous problems. Expert systems differ from conventional computer programs as they combine facts with rules that state relations between the facts to achieve a crude form of reasoning analogous to